Pioneer Biotech

Precision, proven in the operating room.

The A1 Stereotactic Frame reaches both cerebral hemispheres in a single session — with sub-millimetre accuracy, no skull pins, and a patient experience that is measurably better from setup to recovery.

<1mm
Mean trajectory accuracy
50%
Reduction in average operative time
2
Hemispheres accessed at the same time
Zero
Visible pin scars
“What once required two procedures now takes one — with no skull pins, faster setup, and a patient experience that is meaningfully better from start to finish.”

Dr. Mohamed Elsaeed, Director of Functional Neurosurgery

Where the evidence concentrates.

Across clinical use, the A1 Frame’s advantages cluster in three areas that matter most to surgical teams and patients alike.

Targeting accuracy

The frame’s physically reachable reference point and re-zeroing mechanism support consistent sub-millimetre trajectory accuracy, verified mechanically rather than reconstructed from software alone.

Operative efficiency

Simultaneous bilateral access removes an entire surgical session, a second anaesthesia event, and a separate recovery — cutting average operative time for bilateral procedures roughly in half.

Patient experience

Pin-free fixation behind the hairline leaves no visible scars, keeps the airway fully accessible for anaesthesia, and suits claustrophobic and awake patients who struggle with enclosing frames.

The evidence base.

Clinical evaluation of the A1 Frame is ongoing across partner institutions. Published findings, case series, and evaluation summaries are listed here as they are confirmed.

Internal evaluation

Bilateral procedure time in functional neurosurgery

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Institution · Year
Case series

Targeting accuracy with a physically reachable reference point

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Institution · Year
Patient outcomes

Cosmetic and recovery outcomes without skull pins

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Institution · Year

Institutional evaluations are open globally. Clinical teams interested in contributing data are welcome to contact us.

In the words of surgeons.

Being able to treat both sides in one session changed how I plan bilateral cases entirely.

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Placeholder — Role, Institution

The absence of skull pins made the biggest difference for my awake patients — far less anxiety going in.

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Placeholder — Role, Institution

FAQ

Frequently asked questions

Bring the simplest precision to your operating room.

Request a clinical evaluation kit or speak with our team about the evidence behind the A1 Stereotactic Frame.